RESEARCH PAPER
Analysis of Pioneering Computable Biomedical
Knowledge Repositories and their Emerging
Governance Structures
Philip Sahr Amara1†, Marisa Conte2, Allen Flynn1, Jodyn Platt1, Marie Grace Trinidad3
1Department of Learning Health Sciences, University of Michigan Medical School, Michigan 48109-0624, USA
2Taubman Health Sciences Library University of Michigan, Michigan 48109-1382, USA
3School of Public Health, University of Michigan, Michigan 48109-2029, USA
Keywords: Computable Biomedical Knowledge; Governance; Repository; Trust; Sustainability
Citation: Amara, P.S., et al.: Analysis of Pioneering Computable Biomedical Knowledge Repositories and their Emerging
Governance Structures. Data Intelligence 4(3), 653-670 (2022). doi: 10.1162/dint_a_00148
Received: Sept. 10, 2021; Revised: Jan. 18, 2022; Accepted: Feb. 10, 2022
ABSTRACT
A growing interest in producing and sharing computable biomedical knowledge artifacts (CBKs) È
increasing the demand for repositories that validate, catalog, and provide shared access to CBKs. Tuttavia,
there is a lack of evidence on how best to manage and sustain CBK repositories. in questo documento, we present the
results of interviews with several pioneering CBK repository owners. These interviews were informed by the
Trusted Repositories Audit and Certification (TRAC) framework. Insights gained from these interviews suggest
that the organizations operating CBK repositories are somewhat new, that their initial approaches to repository
governance are informal, and that achieving economic sustainability for their CBK repositories is a major
challenge. To enable a learning health system to make better use of its data intelligence, future approaches
to CBK repository management will require enhanced governance and closer adherence to best practice
frameworks to meet the needs of myriad biomedical science and health communities. More effort is needed
to find sustainable funding models for accessible CBK artifact collections.
† Corresponding author: Philip Sahr Amara (E-mail: amaphili
